oxoglutarate dehydrogenase (succinyl-transferring) activity [GO_0004591]

Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + 2-oxoglutarate + H+ = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + CO2.
Tags:

oxoglutarate dehydrogenase (succinyl-transferring) activity

ID: GO_0004591

Class

Catalysis of the reaction: N(6)-[(R)-lipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + 2-oxoglutarate + H+ = N(6)-[(R)-S(8)-succinyldihydrolipoyl]-L-lysyl-[dihydrolipoyllysine-residue succinyltransferase] + CO2.

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Classification

Alternative Names

Synonym Scope Reference
oxoglutarate decarboxylase activity related synonym 1.2.4.2
oxoglutarate dehydrogenase activity related synonym 1.2.4.2
AKGDH activity related synonym 1.2.4.2
alpha-ketoglutaric dehydrogenase activity related synonym 1.2.4.2
OGDC activity related synonym 1.2.4.2
ketoglutaric dehydrogenase activity related synonym 1.2.4.2
2-oxoglutarate:lipoamide 2-oxidoreductase (decarboxylating and acceptor-succinylating) activity related synonym 1.2.4.2
2-oxoglutarate: lipoate oxidoreductase activity related synonym 1.2.4.2
2-ketoglutarate dehydrogenase activity related synonym 1.2.4.2
alpha-ketoglutaric acid dehydrogenase activity related synonym 1.2.4.2
2-oxoglutarate dehydrogenase activity related synonym 1.2.4.2
alpha-ketoglutarate dehydrogenase activity related synonym 1.2.4.2
alpha-oxoglutarate dehydrogenase activity related synonym 1.2.4.2
2-oxoglutarate:dihydrolipoyllysine-residue succinyltransferase-lipoyllysine 2-oxidoreductase (decarboxylating, acceptor-succinylating) related synonym 1.2.4.2
oxoglutarate dehydrogenase (lipoamide) activity exact synonym

References