ribonuclease III activity GO_0004525
ribonuclease III activity
ID: GO_0004525
Class
Catalysis of the endonucleolytic cleavage of RNA with 5'-phosphomonoesters and 3'-OH termini; makes two staggered cuts in both strands of dsRNA, leaving a 3' overhang of 2 nt.
Open in VFB 3D Browser →Classification
- RNA endonuclease activity producing 5’-phosphomonoesters, hydrolytic mechanism
- double-stranded RNA-specific ribonuclease activity
Alternative Names
| Synonym | Scope | Reference |
|---|---|---|
| ribonuclease 3 activity | related synonym | 3.1.26.3 |
| RNase III activity | related synonym | 3.1.26.3 |
| pre-mRNA 3’-end processing endonuclease | narrow synonym |