adult CB0991 neuron [FBbt_20004678]

Adult interneuron with its soma in the subesophageal zone and pre- and post-synapses bilaterally in the flange and superior medial protocerebrum (Gonzalez Segarra et al., 2023; Dorkenwald et al., 2024; Schlegel et al., 2024). It is a putative embryonic-born neuron (Dorkenwald et al., 2024; Schlegel et al., 2024) and it is predicted to be cholinergic (Eckstein et al., 2024). There are four of these cells per brain (Gonzalez Segarra et al., 2023). They are involved in regulating water intake (Gonzalez Segarra et al., 2023).

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adult CB0991 neuron

adult CB0991 neuron

adult CB0991 neuron

adult CB0991 neuron

adult CB0991 neuron

ID: FBbt_20004678

Adult Cholinergic Nervous system

Adult interneuron with its soma in the subesophageal zone and pre- and post-synapses bilaterally in the flange and superior medial protocerebrum (Gonzalez Segarra et al., 2023; Dorkenwald et al., 2024; Schlegel et al., 2024). It is a putative embryonic-born neuron (Dorkenwald et al., 2024; Schlegel et al., 2024) and it is predicted to be cholinergic (Eckstein et al., 2024). There are four of these cells per brain (Gonzalez Segarra et al., 2023). They are involved in regulating water intake (Gonzalez Segarra et al., 2023).

CB0991 from Schlegel et al. (2024) mapped to CCHa2R-RA based on annotations in FlyWire v783. Pre- and post-synapses are based on assertions in (Gonzalez Segarra et al., 2023) as well as data in FlyWire v783 (Dorkenwald et al., 2024; Schlegel et al., 2024).

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## Classification

Relationships

bearer of: bilateral
has soma location: cell body rind of adult subesophageal zone
receives synaptic input in region: flange, superior medial protocerebrum
sends synaptic output to region: flange, superior medial protocerebrum

Alternative Names

Synonym	Scope	Reference
CB0991	exact synonym	Schlegel et al., 2024
PRW075	exact synonym	Berg et al., 2025
CB0991	exact synonym	Bates et al., 2025
adult CCHa2R-RA neuron	exact synonym	González Segarra et al., 2023
PRW075	exact synonym

List all available images of adult CB0991 neuron (14 total)

Thumbnail	Name	Tags
	FLA.SMP.10	Nervous_system, Adult, Cholinergic
	PRW075_L (MaleCNS:137770)	Nervous_system, Adult, Cholinergic
	PRW075_L (MaleCNS:29215)	Nervous_system, Adult, Cholinergic
	PRW075_R (MaleCNS:31778)	Nervous_system, Adult, Cholinergic
	PRW075_R (MaleCNS:567159)	Nervous_system, Adult, Cholinergic

View all 14 results in VFB →

Downstream connectivity classes for adult CB0991 neuron (142 total)

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View all 142 results in VFB →

Upstream connectivity classes for adult CB0991 neuron (28 total)

Thumbnail	Name	Tags

View all 28 results in VFB →

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tyle="display:flex;"> "Cell", "Class", "Nervous_system", "Neuron", "has_subClass", "hasScRNAseq" ], "short_form": "FBbt_00052046", "unique_facets": [ "Adult", "Nervous_system", "Neuron" ], "label": "adult interneuron" } ], "relationships": [ { "relation": { "iri": "http://purl.obolibrary.org/obo/RO_0013003", "label": "sends synaptic output to region", "type": "sends_synaptic_output_to_region" }, "object": { "symbol": "", "iri": "http://purl.obolibrary.org/obo/FBbt_00007055", "types": [ "Entity", "Adult", "Anatomy", "Class", "Nervous_system", "Synaptic_neuropil", "Synaptic_neuropil_domain" ], "short_form": "FBbt_00007055", "unique_facets": [ "Adult", "Nervous_system", "Synaptic_neuropil_domain" ], "label": "superior medial protocerebrum" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/RO_0013003", "label": "sends synaptic output to region", "type": "sends_synaptic_output_to_region" }, "object": { "symbol": "", "iri": "http://purl.obolibrary.org/obo/FBbt_00045050", "types": [ "Entity", "Adult", "Anatomy", "Class", "Nervous_system", "Synaptic_neuropil", "Synaptic_neuropil_domain" ], "short_form": "FBbt_00045050", "unique_facets": [ "Adult", "Nervous_system", "Synaptic_neuropil_domain" ], "label": "flange" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/RO_0013002", "label": "receives synaptic input in region", "type": "receives_synaptic_input_in_region" }, "object": { "symbol": "", "iri": "http://purl.obolibrary.org/obo/FBbt_00007055", "types": [ "Entity", "Adult", "Anatomy", "Class", "Nervous_system", "Synaptic_neuropil", "Synaptic_neuropil_domain" ], "short_form": "FBbt_00007055", "unique_facets": [ "Adult", "Nervous_system", "Synaptic_neuropil_domain" ], "label": "superior medial protocerebrum" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/RO_0013002", "label": "receives synaptic input in region", "type": "receives_synaptic_input_in_region" }, "object": { "symbol": "", "iri": "http://purl.obolibrary.org/obo/FBbt_00045050", "types": [ "Entity", "Adult", "Anatomy", "Class", "Nervous_system", "Synaptic_neuropil", "Synaptic_neuropil_domain" ], "short_form": "FBbt_00045050", "unique_facets": [ "Adult", "Nervous_system", "Synaptic_neuropil_domain" ], "label": "flange" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/RO_0002100", "label": "has soma location", "type": "has_soma_location" }, "object": { "symbol": "", "iri": "http://purl.obolibrary.org/obo/FBbt_00049781", "types": [ "Entity", "Adult", "Anatomy", "Class", "Nervous_system" ], "short_form": "FBbt_00049781", "unique_facets": [ "Adult", "Nervous_system" ], "label": "cell body rind of adult subesophageal zone" } }, { "relation": { "iri": "http://purl.obolibrary.org/obo/RO_0000053", "label": "bearer of", "type": "bearer_of" }, "object": { "symbol": "", "iri": "http://purl.obolibrary.org/obo/PATO_0000618", "types": [ "Entity", "Class" ], "short_form": "PATO_0000618", "unique_facets": [ "Class" ], "label": "bilateral" } } ], "xrefs": [], "anatomy_channel_image": [], "pub_syn": [ { "synonym": { "scope": "has_exact_synonym", "label": "adult CCHa2R-RA neuron", "type": "" }, "pub": { "core": { "symbol": "", "iri": "http://flybase.org/reports/FBrf0257621", "types": [ "Entity", "Individual", "pub" ], "short_form": "FBrf0257621", "unique_facets": [ "pub" ], "label": "Gonz\u00e1lez Segarra et al., 2023, eLife 12: RP88143" }, "FlyBase": "FBrf0257621", "PubMed": "37732734", "DOI": "10.7554/eLife.88143" } } ], "def_pubs": [ { "core": { "symbol": "", "iri": "http://flybase.org/reports/FBrf0257621", "types": [ "Entity", "Individual", "pub" ], "short_form": "FBrf0257621", "unique_facets": [ "pub" ], "label": "Gonz\u00e1lez Segarra et al., 2023, eLife 12: RP88143" }, "FlyBase": "FBrf0257621", "PubMed": "37732734", "DOI": "10.7554/eLife.88143" } ] }

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