pro-RAS proteins are farnesylated [GO_0004660]
Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate. The catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein. There is no relationship between this activity and farnesyltransferase activity, GO:0004311, where the catalyzed reaction forms (free) geranylgeranyl diphosphate.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen pro-RAS proteins are farnesylated in VFB
VFB Term Json
{
"term": {
"core": {
"iri": "http://purl.obolibrary.org/obo/GO_0004660",
"symbol": "",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0004660",
"label": "pro-RAS proteins are farnesylated"
},
"description": [
"Catalysis of the reaction: farnesyl diphosphate + protein-cysteine = S-farnesyl protein + diphosphate."
],
"comment": [
"The catalyzed reaction transfers a farnesyl group from farnesyl diphosphate to a target protein. There is no relationship between this activity and farnesyltransferase activity, GO:0004311, where the catalyzed reaction forms (free) geranylgeranyl diphosphate."
]
},
"query": "Get JSON for Class",
"version": "44725ae",
"parents": [
{
"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0008318",
"types": [
"Entity",
"Class"
],
"short_form": "GO_0008318",
"label": "protein prenyltransferase activity"
}
],
"relationships": [],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
"scope": "has_exact_synonym",
"label": "protein-cysteine farnesyltransferase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
"Entity",
"Individual",
"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
},
{
"synonym": {
"scope": "has_narrow_synonym",
"label": "CAAX farnesyltransferase activity",
"type": ""
},
"pub": {
"core": {
"symbol": "",
"iri": "http://flybase.org/reports/Unattributed",
"types": [
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"pub"
],
"short_form": "Unattributed",
"label": ""
},
"FlyBase": "",
"PubMed": "",
"DOI": ""
}
}
],
"def_pubs": []
}
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