sigma factor activity [GO_0016987]
Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
Note
This page displays the raw VFB json record for this term. Please use the link below to open the term inside the Virtual Fly Brain viewerOpen sigma factor activity in VFB
Term Information
- ID: GO_0016987
- Name: sigma factor activity
- Definition: Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins.
- Synonyms:
- Type:
- Comment:
VFB Term Json
{
"term": {
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"symbol": "",
"types": [
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"label": "sigma factor activity"
},
"description": [
"Sigma factors act as the promoter specificity subunit of eubacterial and plant plastid multisubunit RNA polymerases, whose core subunit composition is often described as alpha(2)-beta-beta-prime. Although sigma does not bind DNA on its own, when combined with the core to form the holoenzyme, the sigma factor binds specifically to promoter elements. The sigma subunit is released once elongation begins."
],
"comment": []
},
"query": "Get JSON for Class",
"version": "275438e",
"parents": [
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"symbol": "",
"iri": "http://purl.obolibrary.org/obo/GO_0003700",
"types": [
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"short_form": "GO_0003700",
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"label": "DNA-binding transcription factor activity"
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"label": "regulation of DNA-templated transcription initiation"
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"label": "core promoter sequence-specific DNA binding"
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"label": "RNA polymerase core enzyme binding"
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}
],
"xrefs": [],
"anatomy_channel_image": [],
"pub_syn": [
{
"synonym": {
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"label": "bacterial sigma factor activity",
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},
{
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},
{
"synonym": {
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},
{
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"label": ""
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"FlyBase": "",
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},
{
"synonym": {
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"label": "core DNA-dependent RNA polymerase binding promoter specificity activity",
"type": ""
},
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"label": ""
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},
{
"synonym": {
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"label": "plastid sigma factor activity",
"type": ""
},
"pub": {
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"def_pubs": []
}
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