Sirt1 [FBgn0024291]

[Silent information regulator 2; sirtuin 2; Positive Regulators of Notch Signaling Pathway; SIRT1; p53 binding; Sirt1/dSir2; CG5216; l(2)05326; sir2; Sirt1; enables; material entity; D.mel1; DSir2; sirt1; dsir2; BEST:LD38188; dmSRT406; NAD+ binding; Sir2L; SIR-2; transcription corepressor activity; NAD-dependent histone deacetylase activity; SIRTUIN LYSINE DEACETYLASES; is part of; gene; dSIR2; Sirtuin 1; SIR2; transcription factor binding]

Open Sirt1 in VFB

VFB Term Json

{
    "term": {
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            "iri": "http://flybase.org/reports/FBgn0024291",
            "symbol": "",
            "types": [
                "Entity",
                "Class",
                "Gene"
            ],
            "short_form": "FBgn0024291",
            "label": "Sirt1"
        },
        "description": [],
        "comment": []
    },
    "query": "Get JSON for Class",
    "version": "44725ae",
    "parents": [
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/BFO_0000040",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "BFO_0000040",
            "label": "material entity"
        },
        {
            "symbol": "",
            "iri": "http://purl.obolibrary.org/obo/SO_0000704",
            "types": [
                "Entity",
                "Class"
            ],
            "short_form": "SO_0000704",
            "label": "gene"
        }
    ],
    "relationships": [
        {
            "relation": {
                "iri": "http://purl.obolibrary.org/obo/RO_0002327",
                "label": "enables",
                "type": "enables"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0002039",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0002039",
                "label": "p53 binding"
            }
        },
        {
            "relation": {
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                "label": "enables",
                "type": "enables"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0017136",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0017136",
                "label": "NAD-dependent histone deacetylase activity"
            }
        },
        {
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                "label": "enables",
                "type": "enables"
            },
            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0003714",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0003714",
                "label": "transcription corepressor activity"
            }
        },
        {
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                "label": "enables",
                "type": "enables"
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            "object": {
                "symbol": "",
                "iri": "http://purl.obolibrary.org/obo/GO_0070403",
                "types": [
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                    "Class"
                ],
                "short_form": "GO_0070403",
                "label": "NAD+ binding"
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        },
        {
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            "object": {
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                "iri": "http://purl.obolibrary.org/obo/GO_0008134",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "GO_0008134",
                "label": "transcription factor binding"
            }
        },
        {
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                "label": "is part of",
                "type": "part_of"
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            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgg0001069",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgg0001069",
                "label": "Positive Regulators of Notch Signaling Pathway"
            }
        },
        {
            "relation": {
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                "label": "is part of",
                "type": "part_of"
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            "object": {
                "symbol": "",
                "iri": "http://flybase.org/reports/FBgg0000278",
                "types": [
                    "Entity",
                    "Class"
                ],
                "short_form": "FBgg0000278",
                "label": "SIRTUIN LYSINE DEACETYLASES"
            }
        }
    ],
    "xrefs": [],
    "anatomy_channel_image": [],
    "pub_syn": [
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "CG5216",
                "type": ""
            },
            "pub": {
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                        "pub"
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Sirt1/dSir2",
                "type": ""
            },
            "pub": {
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "DSir2",
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            },
            "pub": {
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                    "short_form": "Unattributed",
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                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "D.mel1",
                "type": ""
            },
            "pub": {
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "SIRT1",
                "type": ""
            },
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                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "l(2)05326",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Sir2L",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "sirt1",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "sir2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dmSRT406",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Sirtuin 1",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "SIR2",
                "type": ""
            },
            "pub": {
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Sir2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "SIR-2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dSIR2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "BEST:LD38188",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dsir2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Silent information regulator 2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
                    "iri": "http://flybase.org/reports/Unattributed",
                    "types": [
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                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "sirtuin 2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "types": [
                        "Entity",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "dSir2",
                "type": ""
            },
            "pub": {
                "core": {
                    "symbol": "",
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                    "types": [
                        "Entity",
                        "Individual",
                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        },
        {
            "synonym": {
                "scope": "has_exact_synonym",
                "label": "Sirt1",
                "type": ""
            },
            "pub": {
                "core": {
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                    "iri": "http://flybase.org/reports/Unattributed",
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                        "pub"
                    ],
                    "short_form": "Unattributed",
                    "label": ""
                },
                "FlyBase": "",
                "PubMed": "",
                "DOI": ""
            }
        }
    ],
    "def_pubs": []
}